Web26 aug. 2024 · Atherosclerotic vascular disease is the major cause of myocardial infarctions, strokes, peripheral vascular disease and other illnesses that collectively … WebI investigated quantitative protein changes in primary human endothelial cells. Using a proteomic approach, I SILAC-labelled endothelial cells (HUVEC) and looked into the interaction with THP-1 monocytes and platelets in response to inflammatory stimuli. Inflammation is the onset of atherosclerosis, a cardiovascular disease. I
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WebCardiovascular Research 1 december 2015. Neointimal hyperplasia is a common feature of fibro-proliferative vascular disease and characterizes initial stages of atherosclerosis. Neointimal lesions mainly comprise smooth muscle-like cells. The presence of these lesions is related to local differences in shear stress. Web6 dec. 2024 · Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk. seether net worth
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Web6 mrt. 2015 · Conclusion: Ang-(1-7) attenuates Ang II-induced ICAM-1, VCAM-1, and MCP-1 expression via the MAs receptor by suppressing the P38 and NF-κB pathways in HUVECs. Ang-(1-7) might delay the progression of inflammatory diseases, including atherosclerosis. © 2015 S. Karger AG, Basel Introduction Web12 dec. 2024 · HUVECs were incubated in the absence or presence of 1, and 3% concentrations of sevoflurane for various time-points and cell viability was determined by MTT assay. Values represent the means ± SD of triplicate measurements. *P<0.05 of 1% sevoflurane vs. the control group; #P<0.05 of 3% sevoflurane vs. the control group. WebHuman umbilical vein endothelial cells (HUVEC) are a valuable in vitro model that has contributed significantly to major insights in regulation of endothelial cell function and angiogenesis or the pathophysiology of atherosclerosis and plaque formation. Applications • Screening for pro- or anti-angiogenic factors seether music genre