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Metalloreductase steap4

Web17 aug. 2024 · Domain-swapped, trimeric STEAP4 orients NADPH bound to a cytosolic domain onto axially aligned flavin-adenine dinucleotide (FAD) and a single b-type heme that cross the transmembrane-domain to … WebSTEAP4 Antibodies. The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+), using NAD (+) as acceptor.

The Steap proteins are metalloreductases Blood - American …

WebBoster Bio Anti-Metalloreductase STEAP4 STEAP4 Antibody catalog # A04760. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 0.1 … Web1 mei 2007 · PTHR14239:SF8 METALLOREDUCTASE STEAP3 1 hit; Pfam. View protein in Pfam; PF03807 F420_oxidored 1 hit; PF01794 Ferric_reduct 1 hit; SUPFAM. SSF51735 NAD(P)-binding Rossmann-fold domains 1 hit; MobiDB. lake norman baseball club https://kriskeenan.com

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Web15 aug. 2006 · Now, through homology, expression, and functional studies, we characterize all 4 members of this protein family and demonstrate that 3 of them, Steap2, Steap3, and … Web14 feb. 2024 · To generate the STEAP4-inducible clone, Flag-tagged human STEAP4 cDNA under the control of Tet-responsive element was transduced into the Ls174t cells along … Web20 aug. 2024 · Abstract. Six-Transmembrane Epithelial Antigen of the Prostate 1-4 (STEAP1-4) compose a family of metalloproteinases involved in iron and copper … lake norman boat yard

STEAP4: its emerging role in metabolism and homeostasis of ... - PubMed

Category:Single cell type - STEAP4 - The Human Protein Atlas

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Metalloreductase steap4

Regulation of hepatic six transmembrane epithelial antigen of …

WebBT LAB 공식대리점 Shanghai Korain Biotech - ANTIBODIES - Rabbi... Web19 dec. 2024 · Six transmembrane epithelial antigen of prostate 4 metalloreductase (STEAP4) was identified as a new marker of synthetic VSMCs. CytoTRACE identified subpopulations with higher differentiation potential in specified cell types including synthetic VSMCs, enolase 1 + fibroblasts and myeloid-derived neutrophils.

Metalloreductase steap4

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WebSteap4 is a cell surface metalloreductase linked to obesity-associated insulin resistance. Initial characterization of its cell surface metalloreductase activity has been reported, but thor-ough biochemical characterization of this activity is lacking. Here, we report detailed kinetic analysis of the Steap4 cell sur-face metalloreductase ... Web28 mei 2010 · STEAP4 is a plasma membrane metalloreductase involved in the transport of iron and copper. Recently, STEAP4 was implicated in promoting insulin sensitivity by acting in white adipose tissue to control the production of …

Web1 sep. 2006 · Steap4 are not only ferrireducta ses, but also cupric reducta ses that stimulate cellular . ... STEAP1 acts as a metalloreductase contributing to the generation of reactive oxygen species, ... WebMetalloreductase STEAP4(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoateFLAVIN-ADENINE DINUCLEOTIDEN-ACETYL-D-GLUCOSAMINENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE. NCBI. National Center for Biotechnology Information. Search. 6HCY: human STEAP4 bound to NADP, FAD, heme and Fe(III) …

WebSteap4 is a cell surface metalloreductase linked to obesity-associated insulin resistance. Initial characterization of its cell surface metalloreductase activity has been reported, but thorough biochemical characterization of this activity is lacking. Here, we report detailed kinetic analysis of the Steap4 cell surface metalloreductase activities. Steap4 shows … Webmetalloreductase STEAP4 six transmembrane prostate protein 2 six-transmembrane epithelial antigen of prostate 4 sixTransMembrane protein of prostate 2 tumor necrosis factor, alpha-induced protein 9 tumor necrosis-alpha …

Web1 apr. 2013 · STEAP4, a gene that encodes a metalloreductase linked to obesity, insulin sensitivity, metabolic homeostasis and inflammation, was highly induced in human adipose cells differentiated in the presence of 1,25D but was minimally affected by 1,25D in undifferentiated precursors.

Web20 apr. 2024 · Here, we report that the metalloreductase, STEAP4, is a key effector molecule that participates and contributes to the pathogenesis of Th17-mediated … lake norman campingWeb20 apr. 2024 · Results: Here, we report that the metalloreductase, STEAP4, is a key effector molecule that participates and contributes to the pathogenesis of Th17-mediated … lake norman boat rampsWeb11 okt. 2004 · Metalloreductase STEAP4 EC number EC:1.16.1.9 ( UniProtKB ENZYME Rhea) 1 publication Alternative names Six-transmembrane epithelial antigen of prostate … lake norman garWeb12 apr. 2024 · Objective STEAP4 (six-transmembrane epithelial antigen of the prostate 4) is a metalloreductase that has been shown previously to protect cells from inflammatory damage. Genetic variants in STEAP4 have been associated with numerous metabolic disorders related to obesity, including putative defects in the acute insulin response to … jeni richardWeb4 dec. 2024 · STEAP4 metalloreductase. Gene ID: 79689, updated on 4-Dec-2024. Gene type: protein coding. Also known as: TIARP; STAMP2; SchLAH; TNFAIP9. See all … lake norman dermatology sugarmanWeb22 okt. 2013 · Zhou et al. (2013)concluded that targeting Steap4, a critical endosomal ferrireductase, may represent a therapeutic strategy for bone diseases caused by iron … lake norman camping cabinsWeb21 mrt. 2024 · STEAP4 (STEAP4 Metalloreductase) is a Protein Coding gene. Diseases associated with STEAP4 include Hepatocellular Carcinoma and Arthritis. Among its … lake norman gun and pawn