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Top2b

WebTOP2B. 这个基因编码一种dna拓扑异构酶,一种在转录过程中控制和改变dna拓扑异构酶状态的酶。. 这种核酶参与了染色体缩合、染色单体分离以及dna转录和复制过程中产生的扭转 …

Target genes of Topoisomerase IIβ regulate neuronal survival and …

WebPUNKTEN. Finde zahlreiche Unternehmen und Dienstleister in deiner Umgebung und bezahle mit deinen Top2BE Punkten! Erhalte Top2Be Punkte für spezielle Leistungen und persönliche Erfolge. Die Mitgliedschaft bei TOP2BE ist GRATIS. Punkten Sie ab sofort täglich regional! Web26. okt 2000 · 说明书全文: 本发明属于生物技术领域,具体地说,本发明描述了一种新的多肽——DNA 拓扑异构酶II-beta(TOP2B)9.02,以及编码此多肽的多核苷酸序列。 本发明 还涉及此多核苷酸和多肽的制备方法和应用。 II型拓扑异构酶的催化功能对于染色体的浓缩、染色单体的分开有着非常重 要的作用,还能够释放 ... install nema 15-40 outlet at home https://kriskeenan.com

CD3 epsilon 靶点蛋白 抗体药物 临床药物信息 - ACROBiosystems …

DNA topoisomerase 2-beta is an enzyme that in humans is encoded by the TOP2B gene. WebGenetic deletion of Top2b in mice causes neural defects including aberrant axonal elongation and branching and perinatal death explained by lack of innervation of the … Web14. mar 2024 · The TOP2B gene encodes a type II topoisomerase, an enzyme that generates transient DNA double-strand breaks to relieve topological stress during DNA replication … jim gaffigan seafood bit

UniProt

Category:Topoisomerase IIβ Mediates Doxorubicin-Induced Cardiotoxicity

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Top2b

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Web1. jan 2024 · Regarding TOP2B mRNA values, no substantial differences between primary PCa and mCRPC were found; however, significant lower expression of TOP2B was observed in primary PCa compared to normal tissues and in small-cell or neuroendocrine PCa compared to adeno-PCa. 3.7. TOP2A interaction network and functional enrichment … WebPlease cite: Sebastian Canzler, Markus Fischer, David Ulbrecht, Nikola Ristic, Peter W Hildebrand, René Staritzbichler: ProteinPrompt: a webserver for predicting protein-protein interactions, bioRxiv 2024.09.03.458859 ProteinPrompt is free for non-commercial users

Top2b

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Web15. dec 2002 · Structural organization of the human TOP2A and TOP2B genes. Naunyn-Schmied. Arch Pharmacol 358 (Suppl.1): R155. Jul 1998 Other authors. Efficacy of Diltiazem ER as Add-on Anti-hypertensive Therapy In Mild to Moderate Hypertension, and Isolated Systolic Hypertension (The TIARA Study) (P398). ASH 19th Annual Scientific Meeting and … WebAll lanes : Anti-Topoisomerase II beta/TOP2B antibody (ab72334) at 0.04 µg/ml Lane 1 : Whole cell lysate from Hela cells at 50 µg Lane 2 : Whole cell lysate from Hela cells at 15 …

WebThrough molecular move simulations, us show here that growing plectonemes resulting from transcription-induced supercoiling have the aptitude to actively push cohesin rings along chromatin filaments. The pushing direction is such that within each topologically associating domain (TAD) cohesin rings fo … Web23. sep 2024 · TOP2B dependency of the cardioprotective effects was probed and supported by experiments with diastereomers of a new DEX derivative. Conclusions: This study strongly supports a new mechanistic paradigm that attributes clinically effective cardioprotection against anthracycline cardiotoxicity to interactions with TOP2B but not …

Web31. aug 2024 · 研究者Sonabend说道,如果你考虑到TOP2B在这些肿瘤亚群中是如何进行表达的,那么在TOP2B升高的肿瘤亚群中,其或许会通过扰乱染色质的结构来调节 ... Web12. apr 2024 · Original Concentration: 120µg/mL. Applications: Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.) Predicted isoelectric point: 8.7. Predicted Molecular Mass: 27.5kDa. Accurate Molecular Mass: 30kDa as determined by SDS-PAGE reducing conditions.

WebTOP2B_HUMAN Uniprot Id Gene Info: Interpro Acc IPR001241 Interpro Acc IPR002205 Uniprot Status Swiss-Prot Gene Categories: DRUGGABLE GENOME Publications: TdgClinicalTrial: Q02880. Version: January-2014 Alternate Names: TOP2B Gene Symbol Gene Info: Target Class Enzymes Target Subclass

WebAnti TOP2B pAb [Catalog No.: ATL-HPA024120] Neurodegeneration Products. CUSABIO dashboard. Fukushima Cancer Gene Overexpressing Cell Lines. ubiquitin proteasome related dashboard. Supplier Spotlight: BioAcademia. purefrex protein synthesis. IVF dashboard. Exosome purification and characterization. jim gaffigan quality time tour promoWeb15. máj 2007 · Top2b activity has recently been shown to play a key role in transcription by creating transient double-stranded DNA breaks in the promoter regions of a number of genes . For example, estrogen-bound ERα directs an activating complex that includes Top2b, polyADP-ribose polymerase 1, and other factors typically associated with DNA repair to a ... jim gaffigan resch centerWeb11. dec 2012 · さらに、 Top2b の心筋細胞特異的ノックアウトマウスは、ドキソルビシンを投与しても進行性の心不全を発症しないことから、ドキソルビシンによる心臓毒性は心 … install neovim plugins windowsWeb15. mar 2024 · Inhibition of NPM or TOP2B abrogated BRG1 recruitment. Furthermore, NPM inhibition and targeting BRG1 restored differentiation when combined with RA. Here, we demonstrate a role for NPM and BRG1 ... install neon lights interiorWeb10. aug 2024 · TOP2B: a shared target for the cardiotoxicity induced by doxorubicin and trastuzumab. Both of doxorubicin and trastuzumab inhibit TOP2B in human … jim gaffigan raleighWeb9. nov 2024 · TOP2B expression was also associated with MYCN expression when we conditioned on del(p3) and age-at-diagnosis using multivariate linear regression (P = 3.3 × … install nero softwareWeb17. feb 2024 · Description: Homo sapiens DNA topoisomerase II beta (TOP2B), transcript variant 1, mRNA. (from RefSeq NM_001330700) RefSeq Summary (NM_001330700): This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as … jim gaffigan seattle 2022